In general, many diabetics have delayed puberty and menstrual disorders. Experimental results show that diabetes can delay and inhibit gonadal development. This may be related to hypothalamic pituitary ─ ─ ─ ─ ovarian shaft has changed. Some people think that, like other organizations, like the pituitary, the cells in normal glucose metabolism and utilization of insulin-dependent, and pituitary sugar utilization obstacles have resulted in reduction of pituitary protein synthesis may be reduced gonadotropin secretion and ovarian dysfunction causes.
In modern endocrinology and gynecology research, more and more facts show that human and animal organism is subject to internal and external environmental impact of a complete, integrated whole. On the endocrine system in the endocrine glands and the relationship between hormones, so that the formation of a fully functional endocrine system, complete the body, any kind of endocrine effects occur, may affect the other endocrine. Ovarian neuroendocrine system is an important part and component. Ovarian function is also bound by other endocrine gland functional state constraints. Diabetes is a pancreatic islet function in the endocrine system diseases, it must also affect the secretion of ovarian function, which appears hormone secretion anomalies arising from a variety of menstrual disorders and other symptoms.
Due to these circumstances, if it has not yet begun development of gonads when suffering from diabetes, then insulin function disorders would certainly be a corresponding impact of the development of ovaries. Therefore, a lower sex hormone levels, menstrual cramps, also the inevitable appearance of pubic hair is relatively delayed.
