Diabetes, glucose metabolism disorder, making male testis interstitial cells (secretion of male hormones) and pituitary cells (secretion of gonadotropin) and other hormone-secreting cells takes place on the barriers to the use of sugar, resulting in synthesis of sex hormones and promote gonadal hormone dysfunction, blood hormone levels in the corresponding decrease, resulting in dysfunction of reproductive endocrine hormone secretion; also could result in sperm motility needed source of energy shortage, seriously affecting the sperm activity. High protein, high fat, high calorie intake and multi-sport lifestyle of sitting lead to less obese increasing surge in the incidence of diabetes. With the increasing incidence of diabetes, younger age, gonadal dysfunction has become a clinical complication that should not be neglected. Gonadal dysfunction is very common in diabetic patients Testosterone and DHT is to maintain the male reproductive function in the main male hormone, puberty, diabetes can cause gonadal retardation, sexuality serious deficiencies, affecting the male gonad and its subsidiary organs, gonadal development, and cause diabetes, sexual and reproductive function barriers. State University of New York to a research report, about 1 / 3 of gonadotropin secretion in men with diabetes there is insufficient hypogonadism. The researchers pointed out that although diabetes the body's total testosterone level lower, but still not clear whether this defect is primary or secondary to. Their average age 54.7 years (28 to 80 years) of 103 patients with diabetes mellitus were observed in patients with an average duration of 7.7 years. The results showed that 33% of the patients had hypogonadism, luteinizing hormone and follicle-stimulating hormone levels were significantly lower. Luteinizing hormone levels and free testosterone levels were positively correlated, total testosterone, free testosterone and body mass index (BMI) was negatively correlated. The researchers believe that lack of gonadotropin secretion in gonadal dysfunction is very common in diabetic patients, the need for in-depth assessment. Studies have shown that gonadal organs of diabetes on the role of obvious damage, and so the capacity of testicular secretion of testosterone decreased significantly, diabetes, significantly reduced the testis, epididymis, seminal vesicles and prostate weight, reduced epididymal sperm count and sexual ability. Hypogonadism may be induced diabetes do With regard to men with diabetes hypogonadism of the reasons, there are two views. Some people think that diabetes may affect the synthesis and secretion of testosterone, plasma testosterone reduces secretion of testicular dysfunction, or reflect the peripheral conversion of testosterone to enhance, this change is secondary to metabolic disorders caused by elevated blood glucose results, and gonadal endocrine cells Premature aging is also related. But it was also expressed that hypogonadism predisposing factor for diabetes. Male hypogonadism with diabetes, a close relationship exists between, on the sex hormones with the relationship between insulin sensitivity should also be studied further. Thus, pairs of male diabetic patients with erectile dysfunction (ED) detection of sex hormone levels in patients is necessary, in the treatment should be given to control blood sugar-based comprehensive treatment. If you want to hormone replacement therapy should be pre-check to the exception of prostate cancer, and pay attention to androgen side effects. Men with diabetes are prone to infertility Is well known that reproductive dysfunction is an important clinical manifestations of diabetes. In recent years, research found that cytokines and apoptosis in the pathogenesis of diabetic damage gonadal axis play an important role. With diabetes growing trend towards younger people, under 40 years old male with diabetes, 25% to 30% of people will occur infertility. In fact, a good mobility of sperm that have the ability to conceive, but the vitality of sperm from the sperm cells to glucose metabolism mainly within the range of complex biochemical events in an orderly manner. Diabetes, glucose metabolism disorder, making male testis interstitial cells (secretion of male hormones) and pituitary cells (secretion of gonadotropin) and other hormone-secreting cells takes place on the barriers to the use of sugar, resulting in synthesis of sex hormones and promote gonadal hormone dysfunction, blood hormone levels in the corresponding decrease, resulting in dysfunction of reproductive endocrine hormone secretion; also could result in sperm motility needed source of energy shortage, seriously affecting the sperm activity. In addition, diabetes is often associated with testicular and accessory gland small artery vascular lesions, long-term shortage of blood supply is not only the ability to produce sperm testicular recession, and undermine the glandular secretion of the corresponding function, the results of sperm quality and quantity decline, causing infertility. If the completion of sexual activity associated with the arteries, veins and nerves have been eroded diabetes, there will be diabetic erectile dysfunction, or ejaculation disorder. As involved the nerve location and the different levels of obstacles to the performance of ejaculation varies from individual to individual differences: the difficulties and do not ejaculate ejaculation, mostly because of the domination ejaculation launched neurogenesis lesions; when the pelvic sympathetic nervous system is damaged, there may be retrograde ejaculation, the semen directly into the bladder, so that can also cause infertility. Aggressive treatment of diabetes is a necessary means to restore fertility Diabetic patients did not receive timely diagnosis and treatment of ED for two main reasons: First, the patient's errors, including the cultural taboos, embarrassment and shy, passive attitude, ED do not understand or sex partner, worried about the cost of treatment, etc.; the second is the doctor's errors, including the cultural taboo to talk about ED are not used to looking down on the importance of ED treatment, self-limited experience, no time, diagnosis, limited resources and so on. Doctors should look for opportunities as the admissions screening ED patients, the Wen Zhen sexual problems as part of routine history taking. Determine the ED exist, they should evaluate whether it is suitable for diabetic sex life. Active control of blood glucose, minimize diabetes on blood vessels and nervous system sustained damage, the restoration of testicular function in patients with diabetes mellitus and normal sexual function necessary means, in some patients rely solely on this method is expected to receive fertility maintenance or natural recovery.
